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Article

HTRA2 variations in Taiwanese Parkinson's disease.

Journal of neural transmission (Vienna, Austria : 1996) - 1 May 2014

Chen Chiung-Mei, Wu Chun-Hsien, Hsieh Chin-Hsia, Lin Chih-Hsin, Chen I-Cheng, Chen Yi-Chun, Lee Li-Ching, Lee Chi-Mei, Tseng Yung-Che, Lee-Chen Guey-Jen, Wu Yih-Ru

Abstract excerpt

Mutations in HTRA2 have been reported to associate with Parkinson's disease (PD). This study investigates if the genetic variants in HTRA2 contribute to Taiwanese PD. HTRA2 cDNA fragments from 80 patients with early-onset PD (onset ≤50 years) were sequenced. The identified variants were further examined for a cohort of PD and ethnically matched controls. A novel heterozygous R36W was identified in one early-onset...

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Source

Identifiers

PMID: 24337630
DOI: 10.1007/s00702-013-1131-9

Genes

HTRA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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