Article
Genetic analysis of NR4A2 gene in a large population of Han Chinese patients with Parkinson's disease.
European journal of neurology - 1 Mar 2013
Liu H, Tao Q, Deng H, Ming M, Ding Y, Xu P, Chen S, Song Z, Le W
Abstract excerpt
BACKGROUND: NR4A2 gene is a transcription factor crucial for differentiation and survival of midbrain dopamine (DA) neurons, and several variants have been eported to be associated with Parkinson's disease (PD) in the Caucasian population. METHODS: To determine whether there is any association of NR4A2 mutation or variation with PD in the Han Chinese population, we performed a genetic analysis of all the exons...
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