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Article

Global DNA methylation in old subjects is correlated with frailty.

Age (Dordrecht, Netherlands) - 1 Feb 2012

Bellizzi Dina, D'Aquila Patrizia, Montesanto Alberto, Corsonello Andrea, Mari Vincenzo, Mazzei Bruno, Lattanzio Fabrizia, Passarino Giuseppe

Abstract excerpt

Epigenetic variations have been widely described to occur during the aging process. To verify if these modifications are correlated with the inter-individual phenotypic variability of elderly people, we searched for a correlation between global DNA methylation levels and frailty. We found that the global DNA methylation levels were correlated to the frailty status in middle/advanced-aged subjects but not with...

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Identifiers

PMID: 21336567
DOI: 10.1007/s11357-011-9216-6
PMCID: PMC3260357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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