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Article

New Insights into the Genetic Regulation of Homologue Disjunction in Mammalian Oocytes

1 Jan 2011

Abstract excerpt

Mammalian oocytes execute a unique meiotic programme involving 2 arrest stages and an unusually protracted preamble to chromosome segregation during the first meiotic division (meiosis I). How mammalian oocytes successfully navigate their exceptional meiotic journey has long been a question of immense interest. Understanding the minutiae of female mammalian meiosis I is not merely of academic interest as 80-90%...

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PMID: 21335952
DOI: 10.1159/000324118

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