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Advances and surprises in a decade of oocyte meiosis research

15 Jun 2020

Abstract excerpt

Eggs are produced from progenitor oocytes through meiotic cell division. Fidelity of meiosis is critical for healthy embryogenesis - fertilisation of aneuploid eggs that contain the wrong number of chromosomes is a leading cause of genetic disorders including Down's syndrome, human embryo deaths and infertility. Incidence of meiosis-related oocyte and egg aneuploidies increases dramatically with advancing...

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PMID: 32538429
DOI: 10.1042/ebc20190068

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