Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosome Segregation in the Oocyte: What Goes Wrong during Aging

7 Mar 2022

Abstract excerpt

Human female fertility and reproductive lifespan decrease significantly with age, resulting in an extended post-reproductive period. The central dogma in human female reproduction contains two important aspects. One is the pool of oocytes in the human ovary (the ovarian reserve; approximately 106 at birth), which diminishes throughout life until menopause around the age of 50 (approximately 103 oocytes) in women....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Prenatal Screening and Diagnostics
Share to Renal and related cancers
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35270022
DOI: 10.3390/ijms23052880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosome Segregation in the Oocyte: What Goes Wrong during AgingPMID 35270022Read ↗

Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imagingSemantic proximity Read ↗

Why is Chromosome Segregation Error in Oocytes Increased With Maternal Aging?Semantic proximity Read ↗

Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errorsSemantic proximity Read ↗

Recent Insights into Spindle Function in Mammalian Oocytes and Early Embryos1Semantic proximity Read ↗

Age‐dependent aneuploidy in mammalian oocytes instigated at the second meiotic divisionSemantic proximity Read ↗

Oocyte aging: looking beyond chromosome segregation errorsSemantic proximity Read ↗

Meiotic spindle assembly and chromosome segregation in oocytesSemantic proximity Read ↗

Acentriolar spindle assembly in mammalian female meiosis and the consequences of its perturbations on human reproductionSemantic proximity Read ↗

Advances and surprises in a decade of oocyte meiosis researchSemantic proximity Read ↗

Aneuploidy in human eggs: contributions of the meiotic spindleSemantic proximity Read ↗

Age‐dependent integrity of the meiotic spindle assembly checkpoint in females requires Aurora kinase BSemantic proximity Read ↗

Reproductive Ageing: Metabolic contribution to age-related chromosome missegregation in mammalian oocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.