Article
Loss of the histidine kinase DhkD results in mobile mounds during development of Dictyostelium discoideum.
PloS one - 1 Jan 2013
Singleton Charles K, Xiong Yanhua
Abstract excerpt
BACKGROUND: Histidine kinases are receptors for sensing cellular and environmental signals, and in response to the appropriate cue they initiate phosphorelays that regulate the activity of response regulators. The Dictyostelium discoideum genome encodes 15 histidine kinases that function to regulate several processes during the multicellular developmental program, including the slug to culmination transition,...
Topics
- 3',5'-Cyclic-AMP Phosphodiesterases
- Cyclic AMP
- Dictyostelium
- Genome, Protozoan
- Histidine Kinase
- Phenotype
- Protein Kinases
- Protozoan Proteins