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Article

Sequence variations in the FII, FV, F13A1, FGB and PAI-1 genes are associated with differences in myocardial perfusion.

Pharmacogenomics - 1 Feb 2011

Satra Maria, Samara Maria, Wozniak Greta, Tzavara Chara, Kontos Angelos, Valotassiou Varvara, Vamvakopoulos Nikolaos K, Tsougos Ioannis, Aleporou-Marinou Vassiliki, Patrinos George P, Kollia Panagoula, Georgoulias Panagiotis

Abstract excerpt

AIMS: Coronary artery disease (CAD) is a significant cause of morbidity and mortality in modern societies. The association between genetic markers and CAD is still poorly understood. In this study, we evaluated the effect of five genetic variants: Factor V Leiden (FV:c.1691G>A) (rs6025), Factor II prothrombin (FII:c.20210G>A; rs1799963), plasminogen activator inhibitor 1 (PAI-1) -675(4G/5G;...

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Source

Identifiers

PMID: 21332313
DOI: 10.2217/pgs.10.180

Genes

FGB
SDS
CAD
SERPINE1

Variants

rs6025
rs1800790
rs34857375

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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