Article
A pharmacogenetic effect of factor XIII valine 34 leucine polymorphism on fibrinolytic therapy for acute myocardial infarction.
Journal of the American College of Cardiology - 4 Jan 2005
Marín Francisco, González-Conejero Rocío, Lee Kaeng W, Corral Javier, Roldán Vanessa, López Francisca, Sogorb Francisco, Caturla Juan, Lip Gregory Y H, Vicente Vicente
Abstract excerpt
OBJECTIVES: The aim of this study was to evaluate the pharmacogenetic role of the factor XIII (FXIII) valine 34 leucine (Val34Leu) polymorphism in the fibrinolytic therapy of acute myocardial infarction (MI). BACKGROUND: Fibrinolytic therapy is an established treatment for acute MI, but up to 40% of treated patients do not achieve optimal tissue reperfusion. The FXIII Val34Leu polymorphism is one of the most...
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