Article
Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls.
Lancet (London, England) - 25 Feb 2006
Ye Zheng, Liu Eugene H C, Higgins Julian P T, Keavney Bernard D, Lowe Gordon D O, Collins Rory, Danesh John
Abstract excerpt
BACKGROUND: Variants of certain haemostatic genes (such as that encoding factor V Leiden) are involved in the development of venous thrombosis, but studies of such variants in coronary disease have reported apparently conflicting results. We did meta-analyses on seven such haemostatic genetic variants for which the available evidence on each comprises at least 5000 coronary disease cases and at least 5000...
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