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Article

Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease.

American heart journal - 1 Dec 2007

Hlatky Mark A, Quertermous Thomas, Boothroyd Derek B, Priest James R, Glassford Alec J, Myers Richard M, Fortmann Stephen P, Iribarren Carlos, Tabor Holly K, Assimes Themistocles L, Tibshirani Robert J, Go Alan S

Abstract excerpt

BACKGROUND: Only some patients with coronary artery disease (CAD) develop acute myocardial infarction (MI), and emerging evidence suggests vulnerability to MI varies systematically among patients and may have a genetic component. The goal of this study was to assess whether polymorphisms in genes encoding elements of pathways mediating the response to ischemia affect vulnerability to MI among patients with...

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Source

Identifiers

PMID: 18035072
DOI: 10.1016/j.ahj.2007.07.042

Genes

CAD
ANGPT1
THBS1
VEGFA
VEGFC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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