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Article

The association of functional polymorphisms in genes encoding growth factors for endothelial cells and smooth muscle cells with the severity of coronary artery disease.

BMC cardiovascular disorders - 11 Nov 2016

Osadnik Tadeusz, Strzelczyk Joanna Katarzyna, Lekston Andrzej, Reguła Rafał, Bujak Kamil, Fronczek Martyna, Gawlita Marcin, Gonera Małgorzata, Wasilewski Jarosław, Szyguła-Jurkiewicz Bożena, Gierlotka Marek, Gąsior Mariusz

Abstract excerpt

BACKGROUND: Despite the important roles of vascular smooth muscle cells and endothelial cells in atherosclerotic lesion formation, data regarding the associations of functional polymorphisms in the genes encoding growth factors with the severity of coronary artery disease (CAD) are lacking. The aim of the present study is to analyze the relationships between functional polymorphisms in genes encoding basic...

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Source

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Identifiers

PMID: 27835972
DOI: 10.1186/s12872-016-0402-4
PMCID: PMC5106826

Genes

CAD
EGF
FGF2
VEGFA
IGF1
PDGFB
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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