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Article

A PCR-RFLP method for detection of the LNPEP encoding human insulin-regulated aminopeptidase (IRAP) rs4869317 polymorphism.

The Indian journal of medical research - 1 Jul 2016

RamIrez-Expósito MarIa Jesús, MartInez-Martos Jos Manuel, Palomeque Teresa, Lorite Pedro

Abstract excerpt

BACKGROUND & OBJECTIVES: Insulin regulated aminopeptidase (IRAP) has been related to certain pathologies such as breast cancer, Alzheimer΄s disease and septic shock. IRAP is encoded by the leucyl/cystinyl aminopeptidase (LNPEP) gene. The genetic variation in the LNPEP gene has been analyzed in relation with the mortality and vasopressin clearance in septic shock. The LNPEP rs4869317 SNP (single nucleotide...

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Identifiers

PMID: 27834335
DOI: 10.4103/0971-5916.193298
PMCID: PMC5116884

Genes

LNPEP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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