Article
The autism risk genes MET and PLAUR differentially impact cortical development.
Autism research : official journal of the International Society for Autism Research - 1 Feb 2011
Eagleson Kathie L, Campbell Daniel B, Thompson Barbara L, Bergman Mica Y, Levitt Pat
Abstract excerpt
Candidate risk genes for autism spectrum disorder (ASD) have been identified, but the challenge of determining their contribution to pathogenesis remains. We previously identified two ASD risk genes encoding the receptor tyrosine kinase MET and the urokinase plasminogen activator receptor (PLAUR), which is thought to modulate availability of the MET ligand. We also reported a role for Met signaling in cortical...
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