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Article

Cerebellar Purkinje cell p75 neurotrophin receptor and autistic behavior.

Translational psychiatry - 29 Jul 2014

Lotta L T, Conrad K, Cory-Slechta D, Schor N F

Abstract excerpt

The p75 neurotrophin receptor (p75NTR) is normally expressed in cerebellar Purkinje cells throughout the lifespan. Children with autism spectrum behavior exhibit apparent cerebellar Purkinje cell loss. Cerebellar transcriptome changes seen in the murine prenatal valproate exposure model of autism include all of the proteins known to constitute the p75NTR interactome. p75NTR is a modulator of cytoplasmic and...

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Source

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Identifiers

PMID: 25072321
DOI: 10.1038/tp.2014.55
PMCID: PMC4119222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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