Article

Atypical genomic patterning of the cerebral cortex in autism with poor early language outcome

2020-08-18

Abstract excerpt

Cortical regional identities develop through anterior-posterior (A-P) and dorsal-ventral (D-V) prenatal genomic patterning gradients. Here we find that A-P and D-V genomic patterning of cortical surface area (SA) and thickness (CT) is intact in typically developing and autistic toddlers with good language outcome, but is absent in autistic toddlers with poor early language outcome. Genes driving this effect are pr...

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Literature Corpus work: 6b69593c-391a-53e6-8c8c-efae3ce9df89
DOI: 10.1101/2020.08.18.253443

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