Article

Urokinase Receptor uPAR Overexpression in Mouse Brain Stimulates the Migration of Neurons into the Cortex during Embryogenesis

2021-01-01

Abstract excerpt

Abstract The regulation of neuronal migration in the cerebral cortex during embryonic development is one of the most important but underinvestigated processes that determines the correct formation of neural networks and the development of cognitive functions. Mutations of the urokinase receptor (uPAR) gene in mice lead to spontaneous seizures; polymorphisms of the PLAUR gene encoding uPAR in humans are associated...

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Literature Corpus work: ef4730a8-5486-5fd9-9ac8-09e3ddb99bc0
DOI: 10.1134/s1062360421010069

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