Article
Two frequent polymorphisms of angiotensinogen and their association with multiple sclerosis progression rate.
Journal of the neurological sciences - 15 Apr 2011
Hladikova Magdalena, Vašků Anna, Stourač Pavel, Benešová Yvonne, Bednařík Josef
Abstract excerpt
A total of 195 patients with multiple sclerosis (MS) and 126 controls were investigated for angiotensinogen/(-6)A/G, M235T/and angiotensin converting enzyme I/D gene polymorphisms to test their association with MS susceptibility and/or disease progression using Global Multiple Sclerosis Severity Score (MSSS). We demonstrated a significant association of M235T polymorphism with MSSS. The MM homozygotes had the...
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