Article
Angiotensin-converting enzyme I/D gene polymorphism and risk of multiple sclerosis.
Acta neurologica Scandinavica - 1 Dec 2006
Lovrecić L, Ristić S, Starcević-Cizmarević N, Jazbec S S, Sepcić J, Kapović M, Peterlin B
Abstract excerpt
OBJECTIVES: Angiotensin-converting enzyme (ACE) activity is increased in blood and cerebrospinal fluid of patients with multiple sclerosis (MS). In addition, in experimental autoimmune encephalomyelitis (EAE), an animal model of MS, the blockade of ACE suppresses the disease itself. To analyze the genetic association of the ACE gene with MS, we examined ACE gene insertion/deletion (I/D) polymorphism in MS...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
