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Article

Polymorphisms in the angiotensin I converting enzyme (ACE) gene are associated with multiple sclerosis risk and response to Interferon-β treatment.

International immunopharmacology - 1 Nov 2018

Yaeghmaie Rana, Ghafouri-Fard Soudeh, Noroozi Rezvan, Tavakoli Fatemeh, Taheri Mohammad, Ayatollahi Seyed Abdulmajid

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) as a chronic autoimmune demyelinating disorder of the central nervous system has been associated with numerous genetic and environmental factors among them are functional variants within the angiotensin I converting enzyme (ACE) gene. METHODS: In the present study, we genotyped the rs4359 (C/T) and rs1799752 (Insertion (I)/Deletion (D)) of this gene in 391 MS patients and 380...

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Identifiers

PMID: 30218954
DOI: 10.1016/j.intimp.2018.09.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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