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Article

Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system.

Virus research - 1 Apr 2011

Mori Kyoko, Ikeda Masanori, Ariumi Yasuo, Dansako Hiromichi, Wakita Takaji, Kato Nobuyuki

Abstract excerpt

Ribavirin (RBV) is a potential partner of interferon (IFN)-based therapy for patients with chronic hepatitis C. However, to date, its anti-hepatitis C virus (HCV) mechanism remains ambiguous due to the marginal activity of RBV on HCV RNA replication in HuH-7-derived cells, which are currently used as the only cell culture system for robust HCV replication. We investigated the anti-HCV activity of RBV using novel...

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Source

Identifiers

PMID: 21320556
DOI: 10.1016/j.virusres.2011.02.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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