Article
Fine mapping of a psoriasis-susceptibility locus within the HLA class II region by using microsatellite markers in an association study of Japanese cases and controls.
The Tokai journal of experimental and clinical medicine - 20 Mar 2007
Mabuchi Tomotaka, Oka Akira, Iizuka Mariko, Umezawa Yoshinori, Matsuyama Takashi, Kubota Yumiko, Nakayama Juichiro, Terui Tadashi, Ozawa Maki, Yasumoto Shinichiro, Hashimoto Takashi, Ikeda Shigaku, Matsumoto Yoshinari, Sueki Hirohiko, Iijima Masafumi, Kulski Jerzy K, Ozawa Akira
Abstract excerpt
BACKGROUND: The association between psoriasis and the HLA antigens encoded by the Major Histocompatibility Complex (MHC) genomic region is well known, but the role of the HLA class II region in susceptibility to psoriasis is unclear. OBJECTIVE: The purpose of this study is to map the psoriasis-susceptibility locus within the HLA class II region. METHODS: Three hundred seventy five unrelated Japanese patients with...
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