Article
Follow-up analysis of 180 Chinese Han families: identification of a novel locus for psoriasis at 2p22.3-11.2.
The British journal of dermatology - 1 Mar 2008
Sun L D, Yang S, Liu J J, Ren Y Q, Fan X, Xu S X, Zhou L, Yang C J, Xiao F L, Gao M, Cui Y, Du W H, Huang W, Zhang X J
Abstract excerpt
BACKGROUND: Psoriasis is a common inflammatory and hyperproliferative skin disease. The pathogenesis of psoriasis remains obscure. Family and twin studies have suggested a strong genetic susceptibility to psoriasis. Eight linkage loci (PSORS1-7, PSORS9) were identified and accepted by the OMIM and an additional 16 susceptibility loci have been suggested so far. OBJECTIVES: To investigate further three suggested...
Topics
- Adolescent
- Adult
- Age of Onset
- Aged
- Aged, 80 and over
- Asian People
- Child
- Child, Preschool
- China
- Chromosomes, Human
- Disease Susceptibility
- Female
- Follow-Up Studies
- Genetic Linkage