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Article

Genotype of the mutant LDL receptor allele is associated with LDL particle size heterogeneity in familial hypercholesterolemia.

Atherosclerosis - 1 Jan 2006

Hogue Jean-Charles, Lamarche Benoît, Gaudet Daniel, Tremblay André J, Després Jean-Pierre, Gagné Claude, Couture Patrick

Abstract excerpt

Small, dense LDL particles have been associated with an increased risk of coronary artery disease. In order to assess the potential contribution of the genotype of the LDL receptor to LDL particle size heterogeneity in familial hypercholesterolemia (FH), we examined the electrophoretic characteristics of LDL particles in a large cohort of FH heterozygotes and controls. A total of 259 FH heterozygotes and 208...

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Source

Identifiers

PMID: 15899484
DOI: 10.1016/j.atherosclerosis.2005.03.027

Genes

CETP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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