Article
Genetics of LDL particle heterogeneity: from genetic epidemiology to DNA-based variations.
Journal of lipid research - 1 Jun 2004
Bossé Yohan, Pérusse Louis, Vohl Marie-Claude
Abstract excerpt
Substantial evidence exists suggesting that small, dense LDL particles are associated with an increased risk of coronary heart disease. This disease-related risk factor is recognized to be under both genetic and environmental influences. Several studies have been conducted to elucidate the genetic architecture underlying this trait, and a review of this literature seems timely. The methods and strategies used to...
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