Article
The moderating role of the dopamine transporter 1 gene on P50 sensory gating and its modulation by nicotine.
Neuroscience - 28 Apr 2011
Millar A, Smith D, Choueiry J, Fisher D, Albert P, Knott V
Abstract excerpt
Although schizophrenia has been considered primarily a disease of dopaminergic neurotransmission, the role of dopamine in auditory sensory gating deficits in this disorder and their amelioration by smoking/nicotine is unclear. Hypothesizing that individual differences in striatal dopamine levels may moderate auditory gating and its modulation by nicotine, this preliminary study used the mid-latency (P50) auditory...
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