Article
Auditory information processing in rat genotypes with different dopaminergic properties.
Psychopharmacology - 1 Jul 2001
de Bruin N M, van Luijtelaar E L, Cools A R, Ellenbroek B A
Abstract excerpt
RATIONALE: Auditory filtering disturbances, as measured in the sensory gating and prepulse inhibition (PPI) paradigms, have been linked to aberrant auditory information processing and sensory overload in schizophrenic patients. In both paradigms, the response to the second stimulus (S2) is attenuated by an inhibitory effect of the first stimulus (S1). Dopamine (DA) agonists have been found to reduce gating of...
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