Article
Antiviral resistance testing.
Current opinion in infectious diseases - 1 Dec 2014
Smit Erasmus
Abstract excerpt
PURPOSE OF REVIEW: Current genotypic resistance tests fail to amplify drug-resistant minority variants when they are present below 20% of the total virus population. Next-generation sequencing (NGS) addresses this issue and is being introduced into diagnostic laboratories. This review gives an overview of the resistance tests currently used and explores the opportunities and challenges that NGS genotypic...
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