Article
Highly-sensitive allele-specific PCR testing identifies a greater prevalence of transmitted HIV drug resistance in Japan.
PloS one - 1 Jan 2013
Nishizawa Masako, Hattori Junko, Shiino Teiichiro, Matano Tetsuro, Heneine Walid, Johnson Jeffrey A, Sugiura Wataru
Abstract excerpt
BACKGROUND: The transmission of drug-resistant HIV in newly identified infected populations has become an underlying epidemic which can be better assessed with sensitive resistance testing. Since minority drug resistant variants cannot be detected by bulk sequencing, methods with improved sensitivity are required. Thus, the goal of this study was to evaluate if transmitted drug resistance mutations at minority...
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