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Article

Genetically manipulated mouse models of lung disease: potential and pitfalls

24 Dec 2011

Abstract excerpt

Gene targeting in mice (transgenic and knockout) has provided investigators with an unparalleled armamentarium in recent decades to dissect the cellular and molecular basis of critical pathophysiological states. Fruitful information has been derived from studies using these genetically engineered mice with significant impact on our understanding, not only of specific biological processes spanning cell...

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PMID: 22198907
DOI: 10.1152/ajplung.00085.2011

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