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Article

Cations but not anions regulate the responsiveness of kainate receptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 9 Feb 2011

Maclean David M, Wong Adrian Y C, Fay Anne-Marie, Bowie Derek

Abstract excerpt

Kainate-selective ionotropic glutamate receptors are unique among ligand-gated ion channels in their obligate requirement of external anions and cations for activation. Although it is established that the degree of kainate receptor (KAR) activation is shaped by the chemical nature of the agonist molecule, the possible complementary role of external ions has yet to be examined. Here we show that external cations...

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Identifiers

PMID: 21307250
DOI: 10.1523/JNEUROSCI.4314-10.2011
PMCID: PMC6633048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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