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Article

Identification of critical functional determinants of kainate receptor modulation by auxiliary protein Neto2.

The Journal of physiology - 15 Nov 2015

Griffith Theanne N, Swanson Geoffrey T

Abstract excerpt

KEY POINTS: Kainate receptors (KARs) are ionotropic glutamate receptors (iGluRs) that modulate synaptic transmission and intrinsic neuronal excitability. KARs associate with the auxiliary proteins neuropilin- and tolloid-like 1 and 2 (Neto1 and Neto2), which act as allosteric modulators of receptor function impacting all biophysical properties of these receptors studied to date. M3-S2 linkers play a critical role...

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Identifiers

PMID: 26282342
DOI: 10.1113/JP271103
PMCID: PMC4650415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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