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Article

Antidepressant-like responses to lithium in genetically diverse mouse strains

9 Feb 2011

Abstract excerpt

A mood stabilizing and antidepressant response to lithium is only found in a subgroup of patients with bipolar disorder and depression. Identifying strains of mice that manifest differential behavioral responses to lithium may assist in the identification of genomic and other biologic factors that play a role in lithium responsiveness. Mouse strains were tested in the forced swim test (FST), tail suspension test...

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PMID: 21306560
DOI: 10.1111/j.1601-183x.2011.00682.x

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