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Of Mice and Men: The Inter-individual Variability of the Brain's Response to Drugs

1 Feb 2024

Abstract excerpt

Biological variation is ubiquitous in nature. Despite highly standardized breeding and husbandry under controlled environmental conditions, phenotypic diversity exists in laboratory mice and rats just as it does in humans. The resulting inter-individual variability affects various characteristics of animal disease models, including the responsiveness to drugs. Thus, the common practice of averaging data within an...

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PMID: 38355298
DOI: 10.1523/eneuro.0518-23.2024

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