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Article

A genetic screen for mouse mutations with defects in serotonin responsiveness.

Brain research. Molecular brain research - 23 Jul 2003

Weiss Karin C, Kim Dennis Y, Pawson Catherine T, Cordes Sabine P

Abstract excerpt

The serotonergic system plays a key role in regulating basic behaviors. Deficits in serotonergic neurotransmission have been implicated in psychiatric disorders, such as schizophrenia and depression. Here we have optimized a behavioral screen and performed a small scale genetic screen to identify genes involved in serotonin responsiveness in the mouse. Treatment of mice with serotonin, serotonin precursors, or...

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PMID: 12877987
DOI: 10.1016/s0169-328x(03)00205-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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