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Antidepressants and the resilience to early-life stress in inbred mouse strains.

Pharmacogenetics and genomics - 1 Dec 2011

Binder Elke, Malki Karim, Paya-Cano Jose L, Fernandes Cathy, Aitchison Katherine J, Mathé Aleksander A, Sluyter Frans, Schalkwyk Leonard C

Abstract excerpt

RATIONALE: Selecting an effective treatment for patients with major depressive disorder is a perpetual problem for psychiatrists. It is of particular interest to explore the interaction between genetic predisposition and environmental factors. OBJECTIVES: Mouse inbred strains vary in baseline performance in depression-related behaviour tests, which were originally validated as tests of antidepressant response....

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PMID: 22016050
DOI: 10.1097/FPC.0b013e32834b3f35

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FST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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