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Article

Mouse models of glioblastoma for the evaluation of novel therapeutic strategies

1 Jan 2021

Abstract excerpt

Glioblastoma (GBM) is an incurable brain tumor with a median survival of approximately 15 months despite an aggressive standard of care that includes surgery, chemotherapy, and ionizing radiation. Mouse models have advanced our understanding of GBM biology and the development of novel therapeutic strategies for GBM patients. However, model selection is crucial when testing developmental therapeutics, and each...

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PMID: 34466804
DOI: 10.1093/noajnl/vdab100

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