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Article

Invasion and proliferation kinetics in enhancing gliomas predict IDH1 mutation status.

Neuro-oncology - 1 Jun 2014

Baldock Anne L, Yagle Kevin, Born Donald E, Ahn Sunyoung, Trister Andrew D, Neal Maxwell, Johnston Sandra K, Bridge Carly A, Basanta David, Scott Jacob, Malone Hani, Sonabend Adam M, Canoll Peter, Mrugala Maciej M, Rockhill Jason K, Rockne Russell C, Swanson Kristin R

Abstract excerpt

BACKGROUND: Glioblastomas with a specific mutation in the isocitrate dehydrogenase 1 (IDH1) gene have a better prognosis than gliomas with wild-type IDH1. METHODS: Here we compare the IDH1 mutational status in 172 contrast-enhancing glioma patients with the invasion profile generated by a patient-specific mathematical model we developed based on MR imaging. RESULTS: We show that IDH1-mutated contrast-enhancing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24832620
DOI: 10.1093/neuonc/nou027
PMCID: PMC4022227

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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