Article
The impact of phenotypic switching on glioblastoma growth and invasion.
PLoS computational biology - 1 Jan 2012
Gerlee Philip, Nelander Sven
Abstract excerpt
The brain tumour glioblastoma is characterised by diffuse and infiltrative growth into surrounding brain tissue. At the macroscopic level, the progression speed of a glioblastoma tumour is determined by two key factors: the cell proliferation rate and the cell migration speed. At the microscopic level, however, proliferation and migration appear to be mutually exclusive phenotypes, as indicated by recent in vivo...
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