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Article

Role of MMP14 gene polymorphisms in susceptibility and pathological development to hepatocellular carcinoma.

Annals of surgical oncology - 1 Aug 2011

Chen Tzy-Yen, Li Yi-Ching, Liu Yu-Fan, Tsai Chiung-Man, Hsieh Yi-Hsien, Lin Chiao-Wen, Yang Shun-Fa, Weng Chia-Jui

Abstract excerpt

BACKGROUND: Early detection of hepatocellular carcinoma (HCC) is seldom available because of the lack of reliable markers. Matrix metalloproteinase (MMP) 14 is a cell surface proteinase that displays a broad spectrum of activity against extracellular matrix components and promotes the invasion/metastasis of cells. MMP14 is overexpressed in HCC, and the level is correlated with poor overall survival. The purpose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21298348
DOI: 10.1245/s10434-011-1574-x

Genes

MMP14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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