Article
The Contribution of Matrix Metalloproteinase-7 Promoter Genotypes to Hepatocellular Carcinoma Susceptibility.
Anticancer research - 1 Nov 2022
Yueh Te-Cheng, Tsao Hao-Yuan, Chien Wei-Ching, Tsai Chia-Wen, Pei Jen-Sheng, Wu Ming-Hsien, Chen Chou-Pin, Chen Chou-Chen, Wang Zhi-Hong, Mong Mei-Chin, Yang Ya-Chen, Hung Yi-Chih, Bau DA-Tian, Chang Wen-Shin
Abstract excerpt
BACKGROUND/AIM: Metalloproteinase-7 (MMP-7) has been previously found to be up-regulated in hepatocellular carcinoma (HCC) specimens and cells, favoring epithelial-mesenchymal transition. However, the contribution of MMP-7 genotypes to HCC has not been revealed to date. The study aimed to evaluate the contribution of MMP-7 promoter A-181G (rs11568818) and C-153T (rs11568819) genotypes on the risk of HCC in...
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