Article
Impacts of CCL4 gene polymorphisms on hepatocellular carcinoma susceptibility and development.
International journal of medical sciences - 1 Jan 2017
Wang Bin, Chou Ying-Erh, Lien Ming-Yu, Su Chen-Ming, Yang Shun-Fa, Tang Chih-Hsin
Abstract excerpt
Hepatocellular carcinoma (HCC) is the sixth most common cancer globally and the third most common cause of cancer mortality. In Taiwan, HCC is the second leading cause of cancer death. CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment....
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