Article
In vitro and in vivo onco-suppressor activity of normal cells on cells transformed with the H-ras1 oncogene.
In vivo (Athens, Greece) - 1 Jan 2000
Kakkanas A, Spandidos D A
Abstract excerpt
We have investigated mixed cultures of "normal" early passage Balb/c embryo cells and Balb/c 3T3 cells transformed by the human T24 H-ras1 oncogene. The presence of an excess of "Normal" cells could suppress the phenotype of transformed cells in vitro. A similar type of suppression by normal cell...
Topics
- Animals
- Cell Communication
- Cell Division
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Cells, Cultured
- Fibrosarcoma
- Humans
- Mice
- Mice, Inbred BALB C
- Neoplasm Proteins
- Neoplasm Transplantation
- Oncogenes
- Phenotype
- Proto-Oncogene Proteins p21(ras)