Article
In vitro and in vivo onco-suppressor activity of normal cells on cells transformed with the H-ras1 oncogene.
In vivo (Athens, Greece) - 1 Jan 2000
Kakkanas A, Spandidos D A
Abstract excerpt
We have investigated mixed cultures of "normal" early passage Balb/c embryo cells and Balb/c 3T3 cells transformed by the human T24 H-ras1 oncogene. The presence of an excess of "Normal" cells could suppress the phenotype of transformed cells in vitro. A similar type of suppression by normal cells could be shown in vivo on tumors induced by Balb/c 3T3 transformed cells. The suppressing effect of normal cells on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.