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Article

Induction of chemotactic and invasive phenotype in BALB/c 3T3 cells by 1,2-dibromoethane transformation.

Invasion & metastasis - 1 Jan 1993

Adatia R, Albini A, Colacci A, De Giovanni C, Nanni P, Giunciuglio D, Parodi S, Grilli S, Perocco P

Abstract excerpt

1,2-Dibromoethane (DBE), which can act as initiating agent, is capable of inducing a malignant phenotype in BALB/c 3T3 cells. Cells transformed with a single noncytotoxic dose formed more progressive tumors in vivo. Almost all animals (95%) receiving the inoculum of two different transformed clones developed tumors within 1 month. In the control group only 55% of the animals developed tumors after 4 months....

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PMID: 7960576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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