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Article

Molecular pathogenesis of adult brain tumors and the role of stem cells.

Neurologic clinics - 1 Nov 2007

Sauvageot Claire M, Kesari Santosh, Stiles Charles D

Abstract excerpt

Primary brain tumors consist of neoplasms with varied molecular defects, morphologic phenotypes, and clinical outcomes. The genetic and signaling abnormalities involved in tumor initiation and progression of the most prevalent adult primary brain tumors, including gliomas, meningiomas, and medulloblastomas, are described in this article. The current understanding of the cell-of-origin of these neoplasms is...

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Identifiers

PMID: 17964020
DOI: 10.1016/j.ncl.2007.07.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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