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Cancer stem cells in glioma: challenges and opportunities.

1 Oct 2013

Abstract excerpt

The discovery of cancer stem cells in glioma has created a paradigm shift in our understanding of this deadly disease. Glioma stem cells exhibit sustained self-renewal and potent tumorigenic potential and differ from their more differentiated progeny in response to current therapies. Recurrent disease is likely derived from glioma stem cells or progeny reprogrammed to gain stem cell-like phenotypes, indicating...

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PMID: 24634854
DOI: 10.3978/j.issn.2218-676x.2013.08.01

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