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Brain stem cells as the cell of origin in glioma

1 Jan 2014

Abstract excerpt

Glioma incidence rates in the United States are near 20000 new cases per year, with a median survival time of 14.6 mo for high-grade gliomas due to limited therapeutic options. The origins of these tumors and their many subtypes remain a matter of investigation. Evidence from mouse models of glioma and human clinical data have provided clues about the cell types and initiating oncogenic mutations that drive...

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PMID: 24567787
DOI: 10.4252/wjsc.v6.i1.43

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