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Genetic Abnormalities, Clonal Evolution, and Cancer Stem Cells of Brain Tumors

2 Oct 2018

Abstract excerpt

Brain tumors are highly heterogeneous and have been classified by the World Health Organization in various histological and molecular subtypes. Gliomas have been classified as ranging from low-grade astrocytomas and oligodendrogliomas to high-grade astrocytomas or glioblastomas. These tumors are characterized by a peculiar pattern of genetic alterations. Pediatric high-grade gliomas are histologically...

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PMID: 30279357
DOI: 10.3390/medsci6040085

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