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Article

ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation.

Journal of lipid research - 1 May 2011

Stephensen Charles B, Armstrong Patrice, Newman John W, Pedersen Theresa L, Legault Jillian, Schuster Gertrud U, Kelley Darshan, Vikman Susanna, Hartiala Jaana, Nassir Rami, Seldin Michael F, Allayee Hooman

Abstract excerpt

The objective of this study was to determine whether 5-lipoxygenase (ALOX5) gene variants associated with cardiovascular disease affect eicosanoid production by monocytes. The study was a randomized, double-masked, parallel intervention trial with fish oil (5.0 g of fish oil daily, containing 2.0 g of eicosapentaenoic acid [EPA] and 1.0 g of docosahexaenoic acid [DHA]) or placebo oil (5.0 g of corn/soy mixture)....

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Share to Arachidonate 5-Lipoxygenase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eicosapentaenoic Acid

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Source

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Identifiers

PMID: 21296957
DOI: 10.1194/jlr.P012864
PMCID: PMC3073473

Genes

ALOX5

Provenance

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