Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genome-wide association study identifies 41 loci associated with eicosanoid levels

31 Jul 2023

Abstract excerpt

Eicosanoids are biologically active derivatives of polyunsaturated fatty acids with broad relevance to health and disease. We report a genome-wide association study in 8406 participants of the Atherosclerosis Risk in Communities Study, identifying 41 loci associated with 92 eicosanoids and related metabolites. These findings highlight loci required for eicosanoid biosynthesis, including FADS1-3, ELOVL2, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Consumption and Health Effects
Share to Lipid metabolism and biosynthesis
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37524825
DOI: 10.1038/s42003-023-05159-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genome-wide association study identifies 41 loci associated with eicosanoid levelsPMID 37524825Read ↗

GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids.Semantic proximity Read ↗

Population-based genome-wide association study of plasma complex lipid species.Semantic proximity Read ↗

A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study.Semantic proximity Read ↗

Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans.Semantic proximity Read ↗

Genetics of human plasma lipidome: Understanding lipid metabolism and its link to diseases beyond traditional lipidsSemantic proximity Read ↗

The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study.Semantic proximity Read ↗

Genome-wide Association Study of Complex Lipid Species: Results from the Population-based Rhineland StudySemantic proximity Read ↗

Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.Semantic proximity Read ↗

The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: <i>A Mendelian randomization study</i>Semantic proximity Read ↗

Fifty-one novel and replicated GWAS loci for polyunsaturated and monounsaturated fatty acids in 124,024 EuropeansSemantic proximity Read ↗

Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.Semantic proximity Read ↗

Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.